How Liver Disease Manifests Itself on the Legs

6. Redness of the Palms and Soles

Although more common on the hands, some people with liver disease also develop redness on the soles of the feet, known as palmar or plantar erythema. It’s caused by altered blood flow and hormone levels.

7. Muscle Wasting and Weakness

Advanced liver disease can lead to:

  • Thinning of the leg muscles

  • Weakness and fatigue

  • Difficulty walking or standing for long periods

This happens because the body can’t properly process nutrients and proteins.

When to See a Doctor

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