How many people died from COVID-19?
Probably more than 20 million. The World Health Organization has said member countries reported more than 7 million deaths from COVID-19 but the true death toll is estimated to be at least three times higher.
In the U.S., an average of about 900 people a week have died of COVID-19 over the past year, according to the U.S. Centers for Disease Control and Prevention.
The coronavirus continues to affect older adults the most. Last winter in the U.S., people age 75 and older accounted for about half the nation’s COVID-19 hospitalizations and in-hospital deaths, according to the CDC.
“We cannot talk about COVID in the past, since it’s still with us,” WHO director Tedros Adhanom Ghebreyesus said.
What vaccines were made available?
Scientists and vaccine-makers broke speed records developing COVID-19 vaccines that have saved tens of millions of lives worldwide – and were the critical step to getting life back to normal.
Less than a year after China identified the virus, health authorities in the U.S. and Britain cleared vaccines made by Pfizer and Moderna. Years of earlier research — including Nobel-winning discoveries that were key to making the new technology work — gave a head start for so-called mRNA vaccines.
Today, there’s also a more traditional vaccine made by Novavax, and some countries have tried additional options. Rollout to poorer countries was slow but the WHO estimates more than 13 billion doses of COVID-19 vaccines have been administered globally since 2021.
The vaccines aren’t perfect. They do a good job of preventing severe disease, hospitalization and death, and have proven very safe, with only rare serious side effects. But protection against milder infection begins to wane after a few months.
Like flu vaccines, COVID-19 shots must be updated regularly to match the ever-evolving virus — contributing to public frustration at the need for repeated vaccinations. Efforts to develop next-generation vaccines are underway, such as nasal vaccines that researchers hope might do a better job of blocking infection.
Which variant is dominating now?
Genetic changes called mutations happen as viruses make copies of themselves. And this virus has proven to be no different.
Scientists named these variants after Greek letters: alpha, beta, gamma, delta and omicron. Delta, which became dominant in the U.S. in June 2021, raised a lot of concerns because it was twice as likely to lead to hospitalization as the first version of the virus.
Then in late November 2021, a new variant came on the scene: omicron.
“It spread very rapidly,” dominating within weeks, said Dr. Wesley Long, a pathologist at Houston Methodist in Texas. “It drove a huge spike in cases compared to anything we had seen previously.”
But on average, the WHO said, it caused less severe disease than delta. Scientists believe that may be partly because immunity had been building due to vaccination and infections.
“Ever since then, we just sort of keep seeing these different subvariants of omicron accumulating more different mutations,” Long said. “Right now, everything seems to locked on this omicron branch of the tree.”
The omicron relative now dominant in the U.S. is called XEC, which accounted for 45% of variants circulating nationally in the two-week period ending Dec. 21, the CDC said. Existing COVID-19 medications and the latest vaccine booster should be effective against it, Long said, since “it’s really sort of a remixing of variants already circulating.”
